Zaina Adnan
Zvulon Medical Center at Clalit Medical Services, Israel
Title: Simultaneous occurrence of medullary and papillary thyroid micro-carcinomas
Biography
Biography: Zaina Adnan
Abstract
Papillary thyroid micro carcinoma has been demonstrated to present in association with medullary thyroid carcinoma, however, the coexistence of medullary thyroid carcinoma and papillary thyroid carcinoma represent a very rare entity. In recent years, this rarity has been increasingly observed. The pathogenesis is still controversial. Genetic analysis of RET proto-oncogenes in cases of simultaneous papillary thyroid carcinoma and medullary thyroid carcinoma has so far provided conflicting results. Our presentation describes rare cases of simultaneous medullary thyroid carcinoma and papillary thyroid micro carcinoma. These cases were presented in our clinic with unique features and with different ethnicities. Database and literature review will be presented. Our data supports the coexistence of papillary thyroid micro-carcinoma and medullary thyroid carcinoma. Endocrinologists and pathologists should be aware of this entity. Small thyroid nodules should be evaluated preoperatively especially if they are located in the contra lateral thyroid lobe. The pathologist can play a pivotal role in identifying papillary thyroid micro carcinoma in concurrent existence with medullary thyroid carcinoma.